A novel method for measuring the erythrocyte deformability, under oscillatory shear stress.

A novel method for measuring the erythrocyte deformability, under oscillatory shear stress.

A novel apparatus for detecting a subtle decrease in erythrocyte deformability was developed. The oscillatory shape change of erythrocytes was monitored under an oscillatory shear stress (modulating the oscillation frequency in the range of 9-90 dyn/cm2). The ellipsoidal deformation of intact erythrocytes perfectly followed the oscillatory force of up to about 2 Hz, but the diamide-treated cell...

A simple method for measuring erythrocyte deformability.

To pass through the microcirculation red blood cells (RBCs) need to undergo considerable deformation. The increased rigidity of older cells is probably the main cause of their selective trapping by the spleen; and indirect evidence suggests that impaired deformability may be a critical factor in causing diminished peripheral blood flow (Chien et al, 1967; Schmid-Schonbein et al, 1969; Weed, 197...

A method for measuring the critical shear stress of cohesive soils

New optical technique for measuring erythrocyte deformability with the ektacytometer.

The laser light scattered by erythrocytes subjected to a well-defined shear stess can be analyzed with the ektacytometer to obtain information regarding the changes in cell shape due to fluid shear. We describe an optical technique whereby an observed quantitative output derived from a mesurement of light intensity through a spatial filter is related to the change in cellular dimensions that we...

Erythrocyte deformation under shear flow.